Table 2.
Accuracy for the Outcomes across Different Score Thresholds Using the Highest Non–Intensive Care Unit Score for Each Patient
| Score/Threshold | Mortality |
Mortality or ICU Transfer |
||
|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | |
| SIRS | ||||
| ≥1 | 98.9 | 1.2 | 98.6 | 1.1 |
| ≥\2* | 93.8 | 12.3 | 91.0 | 13.0 |
| ≥3 | 77.5 | 43.8 | 67.7 | 45.9 |
| ≥4 | 36.8 | 84.0 | 26.1 | 85.7 |
| qSOFA | ||||
| ≥1 | 95.2 | 11.9 | 92.9 | 12.9 |
| ≥2* | 68.7 | 63.5 | 53.6 | 66.7 |
| ≥3 | 19.0 | 96.0 | 10.4 | 97.0 |
| MEWS | ||||
| ≥1 | 100.0 | 0.0 | 100.0 | 0.0 |
| ≥2 | 96.2 | 5.6 | 96.2 | 6.0 |
| ≥3 | 92.8 | 20.3 | 89.2 | 22.3 |
| ≥4 | 84.7 | 44.1 | 76.1 | 48.4 |
| ≥5* | 71.4 | 65.0 | 59.1 | 70.1 |
| ≥6 | 52.7 | 81.0 | 40.2 | 85.3 |
| ≥7 | 31.3 | 91.6 | 22.2 | 94.4 |
| ≥8 | 17.5 | 96.8 | 11.1 | 98.3 |
| ≥9 | 8.1 | 99.1 | 4.4 | 99.7 |
| NEWS | ||||
| ≥1 | 97.0 | 1.9 | 98.4 | 2.1 |
| ≥2 | 96.9 | 2.9 | 97.6 | 3.0 |
| ≥3 | 96.5 | 6.2 | 96.2 | 6.8 |
| ≥4 | 95.5 | 13.2 | 93.3 | 14.7 |
| ≥5† | 95.1 | 15.0 | 92.6 | 16.7 |
| ≥5 | 93.6 | 23.1 | 89.2 | 25.8 |
| ≥6 | 91.0 | 34.6 | 84.0 | 38.7 |
| ≥7* | 86.6 | 47.5 | 76.5 | 52.7 |
| ≥8 | 79.9 | 60.0 | 66.5 | 65.6 |
| ≥9 | 71.9 | 72.2 | 54.4 | 77.6 |
| ≥10 | 59.2 | 82.3 | 41.4 | 86.9 |
| ≥11 | 46.7 | 89.5 | 29.7 | 93.0 |
| ≥12 | 32.9 | 94.2 | 19.3 | 96.6 |
| ≥13 | 21.6 | 97.3 | 11.0 | 98.6 |
| ≥14 | 12.1 | 98.8 | 5.8 | 99.5 |
| ≥15 | 6.3 | 99.5 | 2.7 | 99.8 |
Definition of abbreviations: ICU = intensive care unit; MEWS = Modified Early Warning Score; NEWS = National Early Warning Score; qSOFA = quick Sepsis-related Organ Failure Assessment; SIRS = Systemic Inflammatory Response Syndrome.
*
Commonly used cutoff thresholds.
†
NEWS total score ≥5 or at least one individual parameter score of 3.