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. 2017 Apr 11;7:46299. doi: 10.1038/srep46299

Table 1. The effect of corylin on LPS-induced liver and kidney damage markers.

  Control DMSO Corylin 20 mg/kg Corylin 40 mg/kg
AST 200 ± 3 619.75 ± 97.39** 333.5 ± 31.25+ 289 ± 34.53+
ALT 46.5 ± 0.5 291.33 ± 85.61* 72.4 ± 5.61+ 69.33 ± 4.18+
BUN 28.4 ± 1.2 150.5 ± 11.93** 41.66 ± 5.44++ 40.3 ± 9.90++
CRE 0.31 ± 0.01 0.93 ± 0.21** 0.26 ± 0.04++ 0.28 ± 0.02++

Female C57BL/6 mice were injected with corylin (20 or 40 mg/kg, i.p.) or vehicle (DMSO) 1 h before LPS injection (50 mg/kg, i.p.), and the blood samples were harvested 20 h after LPS injection. The levels of ALT, AST, BUN and CRE were measured (n = 5). Statistical significance was assessed by one-way ANOVA followed by Tukey post-hoc test and represented as follows: *p < 0.05, **p < 0.01 vs. Control; +p < 0.05, ++p < 0.05 vs. DMSO.