Table 1. The effect of corylin on LPS-induced liver and kidney damage markers.
| Control | DMSO | Corylin 20 mg/kg | Corylin 40 mg/kg | |
|---|---|---|---|---|
| AST | 200 ± 3 | 619.75 ± 97.39** | 333.5 ± 31.25+ | 289 ± 34.53+ |
| ALT | 46.5 ± 0.5 | 291.33 ± 85.61* | 72.4 ± 5.61+ | 69.33 ± 4.18+ |
| BUN | 28.4 ± 1.2 | 150.5 ± 11.93** | 41.66 ± 5.44++ | 40.3 ± 9.90++ |
| CRE | 0.31 ± 0.01 | 0.93 ± 0.21** | 0.26 ± 0.04++ | 0.28 ± 0.02++ |
Female C57BL/6 mice were injected with corylin (20 or 40 mg/kg, i.p.) or vehicle (DMSO) 1 h before LPS injection (50 mg/kg, i.p.), and the blood samples were harvested 20 h after LPS injection. The levels of ALT, AST, BUN and CRE were measured (n = 5). Statistical significance was assessed by one-way ANOVA followed by Tukey post-hoc test and represented as follows: *p < 0.05, **p < 0.01 vs. Control; +p < 0.05, ++p < 0.05 vs. DMSO.