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. 2017 Apr 11;7:46307. doi: 10.1038/srep46307

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(A) The survival of HL-1 cells after transient transfection of Sesns siRNA and Sesns cDNA was monitored by flow cytometry. (B) Quantification of survival rate. Under control conditions, very small fluorescent variations were present in HL-1 cells. Pacing did not significantly change the survival rate of HL-1 cells. The silencing of Sesns by transient transfection of Sesn1/2/3 siRNA did not decrease the survival rate of paced HL-1 cells. The transiently expressed Sesn1/2/3 cDNA significantly enhanced the survival of paced HL-1 cells. n = 6, ^ΔΔP < 0.01 compared with pacing group; ^&&P < 0.01 compared with the pacing + pcDNA3.1 group.