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Cordycepin reduces hepatocyte apoptosis caused by GalN/LPS injection. Murine liver tissues were collected at 5 h after injected with GalN (700 mg/kg)/LPS (15 μg/kg). (a) Hepatocyte apoptosis were measured by TUNEL staining, and the number of apoptotic cells were counted (n = 3). Scale bars: 50 μm. (b) The level of cleaved caspase-3, caspase-8, and caspase-9 and PARP protein expressions were measured as indicated (n = 5). Each value is mean ± SEM. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.
