Figure 4.

Cordycepin prevents oxidative stress induced by GalN/LPS. Murine liver tissues were collected at 5 h after injected with GalN (700 mg/kg)/LPS (15 μg/kg). (a) Hepatic MDA and GSH levels were determined using commercial kits (n = 8). (b) The ROS levels in the liver tissues were visualized by DHE staining and measured by DCF assay (n = 8). Scale bars: 50 μm. (c) Hepatic NOX activity was determined using NADH as substrates (n = 5). Each value is mean ± SEM. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001.