Table 1.
Clinical characterization and MRI study results.
Summary (mean and standard deviation) of subject characteristics, vessel wall thickness, area and lumen area. Vessel wall thickness is significantly thicker in AD-HIES subjects compared to normal controls, but similar to subjects with known CAD. Vessel wall area in AD-HIES is significantly increased than both CAD and normal controls. Lumen area is significantly dilated in AD-HIES compared to CAD subjects but slightly larger than normal subjects (not statistically different).
| AD-HIES (n = 10) | CAD (n = 10) | Normal (n = 8) | |
|---|---|---|---|
| Age (years) | 31.1 (±15.4) | 47.3 (±13.4)* | 29.5 (±9.3)* |
| Framingham (%) | 1 (1.8) | 1.2(1.7) | 0.5 (0.5) |
| Systolic BP (mmHg) | 136 (±12.5) | 125.5 (±14.9) | 121 (±10.8) |
| Diastolic BP (mmHg) | 72.0 (±11) | 74.0 (±8) | 72 (±6.3) |
| BMI (kg/m2) | 26.5 (±3.6) | 26 (±2.8) | 25 (±4.2) |
| Vessel wall thickness (mm) | 1.4 (±0.2)* | 1.3 (±0.2) | 1.1 (±0.1)* |
| Vessel wall area (mm2) | 20.5 (±10)*▪ | 15.8 (±4.3)* | 13 (±3)▪ |
| Lumen area (mm2) | 9.8 (±9.7)* | 4.8 (±2.5)* | 6.1 (±4) |
*▪
Bonferroni-corrected p < 0.05.