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. 2017 Apr 11;4:170043. doi: 10.1038/sdata.2017.43

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse.

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(a) Quantitative methylation analysis of GFP molecules derived from the samples indicated in Fig. 1. In all, 41 CpGs are present in the fragment analysed and are located in the cassette I. The sequence of the cassette I in control or NONREC molecules has been transformed into the recombinant version to compare identical primary sequences. Data were expressed as the mean±s.e.m. (n=41); *P<0.01 (paired t-test) comparing REC versus UNCUT or versus NONREC. (b) Shannon diversity index between REC (red) and NONREC (blue) and control UNCUT (black). (c) Principal component analysis of REC (red) and NONREC (blue) and control UNCUT (black). (d) Methylation content (taxonomy) of REC and NONREC and control UNCUT.