Table 1. Metabolite concentrations.

Metabolite	−rESAT-6	+rESAT-6
G6P	3.7 ± 0.3	14.5 ± 5.0
FBP	0.2 ± 0.02	0.3 ± 0.03
DHAP	24.7 ± 8.8	172.2 ± 23.3
3PG/2PG	164.2 ± 31.3	539.6 ± 70.4
PEP	56.7 ± 2.0	199.4 ± 19.5
Pyruvate	0.3 ± 0.1	0.2 ± 0.05
Citrate	35.7 ± 0.1	40.8 ± 0.3
AcCoA	1.2 ± 0.1	4.0 ± 0.2

PMA- differentiated THP-1 cells were either left untreated (−rESAT-6) or treated with rESAT6 for 3 h (+rESAT-6) and their metabolites were extracted and concentrations determined using Mass spectrometry. The concentrations are in μM for each metabolite. The values are mean ( ± ) S.D obtained from three separate experiments.