Table 1. Correlation between miR-19a expression and clinical parameters in 275 CRC patients.
| Factors | n | Low miR-19a expression (%) | High miR-19a expression (%) | Pvalue |
|---|---|---|---|---|
| Age | 0.873 | |||
| <60 | 142 | 109(76.8) | 33(23.2) | |
| ≥60 | 133 | 101(75.9) | 32(24.1) | |
| Gender | 0.759 | |||
| Male | 152 | 115(75.7) | 37(24.3) | |
| Female | 123 | 95(77.2) | 28(22.8) | |
| Tumor size | 0.239 | |||
| <5 cm | 139 | 102(73.4) | 37(26.6) | |
| ≥5 cm | 136 | 108(79.4) | 28(20.6) | |
| Tumor location | 0.812 | |||
| Colon | 132 | 102(77.3) | 30(22.7) | |
| Rectum | 142 | 108(76.1) | 34(23.9) | |
| Relapse | 0.112 | |||
| Yes | 38 | 33(86.8) | 5(13.2) | |
| No | 233 | 175(75.1) | 58(24.9) | |
| TNM stage | 0.008* | |||
| I | 49 | 39(79.6) | 10(20.4) | |
| II | 99 | 81(81.8) | 18(18.2) | |
| III | 102 | 67(65.7) | 35(34.3) | |
| IV | 25 | 23(92.0) | 2(8.0) | |
| pT | 0.805 | |||
| T1 + T2 | 58 | 45(77.6) | 13(22.4) | |
| T3 + T4 | 217 | 165(76.0) | 52(23.9) | |
| pN | 0.018* | |||
| N0 | 156 | 128(82.1) | 28(17.9) | |
| N1 + N2 | 112 | 78(69.6) | 34(30.4) | |
| pM | 0.054 | |||
| M0 | 250 | 187(74.8) | 63(25.2) | |
| M1 | 25 | 23(92.0) | 2(8.0) |
*P < 0.05, Chi-square test.