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. 2017 Mar 23;69(Suppl 1):S63–S97. doi: 10.1016/j.ihj.2017.03.006

Table 11.

Contraindications to Thrombolysis.

Absolute Relative No Contraindication
Previous ICH or stroke of unknown origin at any time Transient ischemic attack in the preceding 6 months Menstruation
Ischemic stroke in the preceding 6 months Oral anticoagulant therapy Acute Ischemic stroke within 4.5 h
CNS damage or neoplasms or AV malformation Pregnancy or within 1 week postpartum
Recent major trauma/surgery/head injury (within the preceding 3 weeks) Refractory hypertension (systolic >180 mmHg and/or diastolic >100 mmHg)
GI bleeding within the past month Advanced liver disease
Known bleeding disorder (excluding menstration) Infective endocarditis
Aortic dissection Active peptic ulcer
Non-compressible punctures in the past 24 h (e.g. liver biopsy, lumbar puncture) Prolonged or traumatic resuscitation