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. Author manuscript; available in PMC: 2017 Apr 11.
Published in final edited form as: Sci Transl Med. 2016 Mar 16;8(330):330re1. doi: 10.1126/scitranslmed.aad5651

Figure 2. Increased fMRI activity and gray matter volume in the anodal tDCS group compared to the sham treatment group.

Figure 2

Shown are changes in fMRI activation and gray matter volume before and after intervention in stroke patients receiving motor rehabilitation plus anodal tDCS or sham treatment (post>pre, anodal>sham, voxel-wise General Linear Model, p<0.05 corrected). Images are in radiological convention (R – right), and all lesions appear on the left, the target for tDCS (yellow flash). The X or Y coordinates for each brain slice are given below the slice. (A) Brain regions showing increases in fMRI activity during affected hand movement from baseline to immediately post-intervention for the anodal tDCS group versus the sham treatment group. (B) Regions showing greater increases in movement-related fMRI activity for anodal tDCS versus sham group from baseline to one month follow-up. See table S1 for the location and Z statistic of peak voxels from fMRI analysis. (C) Brain regions showing increases in gray matter density as assessed by voxel-based morphometry (VBM), from baseline to immediately post-intervention for the anodal tDCS group versus the sham treatment group.