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. 2017 Apr 4;12:2673–2687. doi: 10.2147/IJN.S131251

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© 2017 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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Micro-CT measurement of bone formation in the rat calvarial defects implanted with HAP/chitosan and WH/chitosan scaffold at 8 weeks after implantation. (A) Top and cross-sectional views of reconstructed images; red arrows point to the HAP/chitosan and WH/chitosan scaffold. (B, C) BMD and BV/TV in the defects implanted with the scaffolds. Mean ± SD; n=3. *Significant difference between groups (P<0.05).

Abbreviations: CT, computed tomography; WH, whitlockite; HAP, hydroxyapatite; hBMSCs, human mesenchymal stem cells; BMD, bone mineral density; BV/TV, bone volume to total bone volume.