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. 2017 Apr 3;11:1107–1113. doi: 10.2147/DDDT.S131866

Table 3.

Adverse effects and drugs used as rescue treatment in the two study groups

Adverse events/treatments Bupivacaine + saline (n=25) Bupivacaine + dex (n=25) Total, n=50 P-value
Sedation, n (%) 0.004
 1 1 (4) 0 1 (2)
 2 24 (96) 17 (68) 41 (82)
 3 0 2 (8) 2 (4)
 4 0 6 (24) 6 (12)
 5 0 0 0
Hypotension, n (%) 23 (95.83) 23 (92) 46 (93.88) 0.51
Bradycardia, n (%) 2 (8.33) 1 (4) 3 (6.12) 0.48
Nausea/vomiting, n (%) 12 (48) 12 (48) 24 (48) 1
Prescribed ephedrine, mg 140 130 270 0.57
Prescribed atropine, mg 1.5 0.7 2.2 0.55
Prescribed ondansetron, mg 6 3 9 0.26
Prescribed pethidine, n (%) 120 30 150 0.04

Abbreviation: Dex, dexmedetomidine.