. 2017 Apr 3;10:1947–1954. doi: 10.2147/OTT.S123042

Table 2.

The correlation between clinicopathologic characteristics and serum CTSB or serum CysC

Characteristic	n	CTSB		CysC		CysC/CTSB
Characteristic	n	Mean ± SD	P-value	Mean ± SD	P-value	Mean ± SD	P-value
Age (years)			0.412^a		0.428^a		0.510^a
≥58.5	28	39.17±2.51		725.34±9.19		18.59±2.65
<58.5	28	37.44±3.26		681.55±13.39		18.08±1.89
Gender			0.341^a		0.212^a		0.635^a
Male	31	39.46±2.34		733.89±11.81		18.55±2.71
Female	25	37.24±4.51		673.61±8.67		17.66±1.94
Pathologic type			0.631^a		0.621^a		0.378^a
SCC	50	38.13±2.61		701.44±16.62		18.42±2.46
ADC	6	39.65±3.64		723.74±13.74		18.22±2.07
Grade			0.459^b		0.771^b		0.169^b
G1	11	37.57±6.98		702.34±13.69		18.71±2.39
G2	25	39.36±2.99		716.35±9.00		18.18±2.28
G3	20	38.32±5.21		688.98±12.33		18.10±1.88
T status			0.008^a		0.459^a		0.001^a
T1 + T2	24	29.35±3.38		693.18±14.62		22.57±2.73
T3 + T4	32	45.12±4.56		711.40±9.88		16.28±1.87
Lymph node metastasis			0.871^a		0.239^a		0.001^a
No	20	38.81±4.71		729.14±8.32		19.36±2.28
Yes	36	38.17±2.86		687.58±11.89		15.28±1.64

Notes:

Mann–Whitney U test,

Kruskal–Wallis test.

Abbreviations: ADC, adenocarcinoma; CTSB, cathepsin B; CysC, cystatin C; IQ, interquartile; SCC, squamous cell carcinoma; SD, standard deviation.