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Physicochemical parameters and Lipinski’s rule of five
| Descriptor | DB1890B | DB1957 | DB1959 |
|---|---|---|---|
| Molecular weight (≤500) | 602.74 | 590.75 | 654.57 |
| LogP (≤5) | 8.34 | 8.32 | 8.16 |
| No of acceptors (≤10) | 7 | 7 | 7 |
| No of donors (≤5) | 4 | 4 | 4 |
| No of rotatable bonds (≤10) | 14 | 12 | 14 |
| Surface area | 263.244 | 255.36 | 262.77 |
