Table 2.

Biochemical analysis (mean ± SD values) at the 56 dpi of mice blood samples from T. cruzi-infected groups treated with 25 mg/kg/day of each AIA

Compound	BUN	ALT	CK
DB1957	61.2±6.51	36.88±6.08	414.67±295.16
DB1959	44.8±11.17	37.5±3.54	151.5±67.18*
DB1890B	47.05±19.87	141±147.08	1,051.5±212.84*

Notes: Reference values for healthy mice (CECAL/Fiocruz): BUN: 18–29, ALT: 28–132, and CK: 68–1,070. Statistical analysis:

^*P=0.03 (DB1959/DB1980B).

Abbreviations: SD, standard deviation; T. cruzi, Trypanosoma cruzi; AIA, arylimidamide; BUN, blood urea nitrogen; ALT, alanine aminotransferase; CK, creatine kinase.