Figure 4. MSNs depolarize in the equivalent of 0.5 μM glutamate.
Voltage traces from MSN recorded in the absence of TTX, picrotoxin, NBQX, and d-serine. Application of 20 μM NMDA, equipotent to 0.5 μM glutamate, led to firing and sustained depolarization. In the same cell, application of 100 μM DL-TBOA resulted in a peak depolarization of 7 mV.