Figure 5.
Photos of pancreatic tumor-bearing mouse after conducted with different PDT irradiating procedures.
Notes: (A) Group 1, mice were intratumorally injected with 5 pmol of QDs-RGD and then irradiated with fiber (630 nm) directly inserted into the tumor for 20 min at a power density of 100 mW/cm2; (B) group 2, mice received a QDs-RGD injection at the same dose, but the laser optical fiber was placed around, and not inserted into, tumors; (C) group 3, mice were irradiated without an injection of QDs-RGD, and the PDT procedure were conducted as same as group 1. Two weeks later, the PDT procedure of every group was conducted once again.
Abbreviations: PDT, photodynamic therapy; QDs, quantum dots; QDs-RGD, QDs conjugated with arginine–glycine–aspartic acid peptide sequence; RGD, arginine–glycine–aspartic acid.