Phylogeny of CipA and CipB. CipA (PF0190) and CipB (PF1408) are shown in boxes. Genes from bacterial sources are underlined, while all others are from archaea. Genes that are homologs of CipA (bold type), CipB (plain), and OppA (underlined) are so indicated. The bar indicates a branch length equivalent to 0.1 changes per amino acid, and bootstrap values greater than 50% are indicated at the appropriate branch points. Abbreviations: AF, Archaeoglobus fulgidus; APE, Aeropyrum pernix; Bsu, B. subtilis; DVU, Desulfovibrio vulgaris; lmo, L. monocytogenes; MA, Methanosarcina acetivorans; MM, Methanosarcina mazei; PAB, Pyrococcus abysii; PAE, Pyrobaculum aerophylum; PH, Pyroccous horikoshii; PF, P. furiosus; PM, Pasteurella multocida; SAG, Streptococcus agalactiae; SPs, S. pyogenes; SSO, Sulfolobus solfataricus; ST, Sulfolobus tokodaii; STM, S. enterica serovar Typhimurium; TM, T. maritima.