Table 2. Summary of all the HUMAMICE transplanted with HLA-A2+/DR1+ hPBMCs.
| Donor A/mouse | mCD45-hCD45+ | hCD45+hCD19+ | hCD45+hCD3+ | hCD3+hCD4+ | hCD3+hCD8+ |
|---|---|---|---|---|---|
| Mouse 1 (5 weeks) | 11.6% | 45.2% | 17.1% | 60.9% | 29.0% |
| Mouse 2 (5 weeks) | 13.4% | 51.9% | 15.4% | 68.3% | 24.6% |
| Mouse 3 (5 weeks) | 15.2% | 56.7% | 18.9% | 52.4% | 22.8% |
| Mouse 4 (8 weeks) | 9.7% | 49.4% | 16.1% | 59.0% | 30.0% |
| Mouse 5 (8 weeks) | 7.1% | 60.8% | 13.2% | 40.9% | 15.8% |
| Donor B/Mouse | |||||
| Mouse 6 (5 weeks) | 19.2% | 69.2% | 14.7% | 63.1% | 20.9% |
| Mouse 7 (5 weeks) | 15.8% | 54.2% | 15.1% | 60.7% | 19.2% |
| Mouse 8 (8 months) | 8.9% | 51.2% | 20.7% | 40.9% | 12.1% |
| Mouse 9 (12 weeks) | 5.4% | 42.1% | 12.2% | 19.5% | 4.5% |