Figure 3.

Kinetics of the TnI rises at increasing cumulative doxorubicin doses in all patients (A) and according to anthracycline type (B). At cumulative doxorubicin doses <200 mg/m², TnI rises above 0.03 ng/mL occur more frequently in the NPLD subgroup (9.3% and 0.6% in the NPLD and DOX subgroups, respectively; p < .001); however, at doses >200 mg/m², the relationship is reversed, with higher frequency in the DOX subgroup (16.0% and 21.4% in the NPLD and DOX subgroups, respectively: p = .047).

Abbreviations: DOX, doxorubicin; NPLD, nonpegylated liposomal doxorubicin; TnI, Troponin I.