TABLE 6.
Envelope and periplasmic genes
Gene | Function | Log2 pH ratioa
|
Classb | ||
---|---|---|---|---|---|
5/7 | 8.7/7 | 8.7/5 | |||
artI | Periplasmic binding protein of Arg transport system | 0.286 | 0.655 | 0.369 | BH |
artM | Arginine periplasmic binding protein | −0.115 | 0.293 | 0.407 | BH |
btuB | B-12 transporter, outer membrane receptor | −0.667 | 0.037 | 0.704 | AL |
cirA | Colicin I receptor production | −0.885 | 0.260 | 1.145 | AL |
clpX | ATPase subunit of ClpXP protease | −0.361 | −0.625 | −0.264 | BL |
cpxA | Periplasmic stress sensor (CpxAR) | −0.461 | 0.230 | 0.691 | AL |
cpxP | CpxAR-regulated periplasmic stress protein | −3.232 | 1.002 | 4.234 | AL |
cpxR | Periplasmic stress response regulator (CpxAR) | −0.662 | 0.590 | 1.251 | AL |
dsbA | Thiol:disulfide interchange, periplasmic | 0.086 | 1.117 | 1.031 | BH |
dsbC | Disulfide bond isomerase, periplasmic chaperone | −0.288 | −0.534 | −0.246 | BL |
fadL | Fatty acid transport, outer membrane | −0.861 | 1.069 | 1.931 | BH |
fecA | Outer membrane ferric citrate receptor | −2.608 | −1.128 | 1.480 | NH |
fecB | Periplasmic ferric citrate-binding protein | −2.842 | −1.538 | 1.304 | NH |
fepA | Ferrienterobactin outer membrane receptor | −0.966 | −0.289 | 0.676 | NH |
fhuD | Ferric hydroxamate binding protein; hydroxamate-dependent iron uptake | −0.767 | −0.180 | 0.587 | AL |
fliY | Cystine-binding protein, periplasmic | 0.233 | −0.252 | −0.484 | AH |
hdeA | Acid periplasmic chaperone | 0.841 | −0.326 | −1.167 | AH |
hdeB | Acid periplasmic protein | 0.782 | −0.622 | −1.404 | AH |
hisJ | High-affinity histidine-binding protein | −0.149 | 0.400 | 0.549 | BH |
hlpA | Periplasmic chaperone for OMPsc | 0.099 | −0.661 | −0.759 | BL |
lamB | Maltoporin, maltose high-affinity uptake; phage lambda receptor | −4.881 | −3.735 | 1.146 | NH |
lon | DNA-binding, ATP-dependent protease | −0.600 | −1.666 | −1.065 | BL |
malE | Maltose-binding protein, periplasmic | −3.425 | −2.933 | 0.491 | NH |
malM | Maltose operon periplasmic protein | −4.643 | −3.780 | 0.863 | NH |
mltB | Membrane-bound murein hydrolase | −0.739 | −0.419 | 0.320 | NH |
nmpC | Outer membrane | −4.012 | −0.051 | 3.961 | AL |
ompF | Outer membrane porin protein 1a | −2.834 | −0.892 | 1.942 | AL |
ompT | Outer membrane protease VII | −0.815 | −1.204 | −0.389 | BL |
ompX | OMP, induces RNAP-sigma E | 1.523 | 0.439 | −1.083 | NL |
oppA | Periplasmic oligopeptide binding protein | 1.358 | 0.406 | −0.953 | NL |
pal | Lipoprotein associated with peptidoglycan | 0.532 | 0.379 | −0.153 | NL |
potD | Spermidine-binding membrane protein; regulates pot | 0.053 | 0.509 | 0.456 | BH |
ppiA | Rotamase; peptidylprolyl-cis-trans-isomerase A | −0.526 | 0.231 | 0.757 | AL |
pstS | High-affinity, periplasmic phosphate binding protein | −2.479 | −2.262 | 0.217 | NH |
rbsB | d-Ribose binding protein, periplasmic | −0.749 | −1.150 | −0.401 | BL |
rseB | Periplasmic, binds RseA; enhances RpoE-RseA cytoplasmic complex formation | 0.631 | −0.105 | −0.736 | AH |
secD | SecDF-YajC inner membrane secretion complex | −0.165 | 0.287 | 0.452 | AL |
surA | Periplasmic outer membrane porin chaperone, stationary phase | 0.310 | 0.209 | −0.101 | NL |
tatA | Twin arginine translocation | 0.043 | 0.679 | −0.636 | BH |
tatB | Twin arginine translocation | 0.075 | 0.446 | 0.372 | BH |
tolB | Group A colicin uptake and tolerance | 0.498 | 0.421 | −0.077 | NL |
tpX | Thiol peroxidase, antioxidant | 0.637 | 0.178 | −0.459 | NL |
tsx | Phage T6, colicin K resistance; nucleoside channel | −0.707 | −0.904 | −0.196 | BL |
ybgF | TolA-binding periplasmic protein | 0.312 | −0.007 | −0.318 | AH |
yceI | Function unknown; periplasmic protein | −0.036 | 1.038 | 1.074 | BH |
yhcN | Periplasmic protein | 3.064 | −1.136 | −4.199 | AH |
Values in boldface indicate significance (α = 0.001).
AH, Acid High; AL, Acid Low; BH, Base High; BL, Base Low; NH, Neutral High; NL, Neutral Low.
OMPs, outer membrane proteins.
RNAP, RNA polymerase.