TABLE 7.

Universal stress and heat shock response genes

Gene	Function	Log2 pH ratioa			Classb
		5/7	8.7/7	8.7/5
ahpC	Alkyl hydroperoxide reductase	1.003	0.436	−0.568	NL
ahpF	NAD(P)H:peroxiredoxin oxidoreductase	0.777	−0.222	−0.999	AH
cfa	Cyclopropane fatty acid synthase; acid resistance in stationary phase	2.075	−0.480	−2.555	AH
clpB	ClpB protease, ATP-dependent chaperone	−0.219	−1.963	−1.744	BL
cysK	Cysteine synthase, o-acetylserine sulfhydrylase A	1.204	1.351	0.147	NL
cysZ	Unknown function	0.440	0.212	−0.228	NL
dinI	Inhibits RecA coprotease	0.132	0.568	0.436	BH
dinJ	Induced by DNA damage	0.683	1.192	0.508	BH
dnaJ	DnaK cochaperone	−0.908	−2.155	−1.247	BL
dnaK	HSP-70-type molecular chaperone	−0.894	−2.249	−1.356	BL
dps	Stress response DNA-binding protein	1.130	0.105	−1.025	NL
grpE	Nucleotide exchange factor for DnaKJ	−0.491	−1.141	−0.650	BL
grxA	Glutaredoxin 1	1.666	−0.106	−1.772	AH
hdeA	Acid periplasmic chaperone	0.841	−0.326	−1.167	AH
hdeB	Acid periplasmic chaperone	0.782	−0.622	−1.404	AH
hslJ	Heat-inducible novobiocin resistance	0.368	−0.676	−1.044	AH
hslU	Heat-inducible ATP-dependent protease	−0.745	−1.688	−0.946	BL
hslV	Heat-inducible ATP-dependent protease	−1.125	−1.913	−0.788	BL
ibpB	Heat-inducible chaperone, HSP20 family	−1.691	−2.618	−0.928	BL
hslO	Hsp33, cytoplasmic heat shock chaperone activated by disulfide bond formation	−1.453	−1.737	−0.284	BL
hslR (yrfH)	Hsp15, heat shock, binds RNA and DNA	−1.773	−1.940	−0.168	NH
katG	Catalase-hydrogen peroxidase I	−0.578	−0.313	0.265	AL
rpoE	RNAPc sigma E, envelope heat stress	0.310	−0.427	−0.738	AH
rpoH	RNAP sigma 32, heat shock regulons	−0.378	0.084	0.462	AL
rseA	Anti-RpoE sigma factor, spans inner membrane	0.419	−0.159	−0.578	AH
rseB	Binds periplasmic domain of anti-RpoE sigma RseA	0.631	−0.105	−0.736	AH
sodB	Superoxide dismutase, Fe; acid inducible	0.752	0.280	−0.472	NL
ycdB	Function unknown, peroxidase homolog	0.654	−0.329	−0.983	AH
ycdO	Acid inducible, function unknown	0.842	−0.625	−1.467	AH
uspD (yiiT)	UV resistance	1.333	−0.497	−1.830	AH

^aValues in boldface indicate significance (α = 0.001).

^bAH, Acid High; AL, Acid Low; BH, Base High; BL, Base Low; NH, Neutral High; NL, Neutral Low.

^cRNAP, RNA polymerase.