FIG. 1.
Alignment of D. nodosus Fur homologues. The FurDn protein was aligned by using ClustalW (59) to its two highest scoring matches as determined by BLASTP (1) as well as to the E. coli and P. aeruginosa Fur proteins. Regions predicted to contain secondary structures are shown (42). Identical residues are shaded black, with similar residues shaded gray. Metal binding site 1 residues are indicated with circles, and site 2 residues are indicated with triangles, as identified from the crystal structure of P. aeruginosa Fur. Residues underlined highlight a motif thought to be involved in DNA binding. Legionella pneumophila (27), accession no. AAA19656.1; Coxiella burnetii (R. Seshadri and J. Samuel, unpublished results), accession no. AAK00303.1; E. coli (52), accession no. P06975; and P. aeruginosa (43), accession no. Q03456.