Table 2.

Rates of healthcare-associated infections stratified by week(s) after hospitalization for burn injury.

		Weeks after admission
	Overall	Week 1	Weeks 2 – 3	Weeks 4+	p-value
Bloodstream infection	1.82 (1.52–2.18)	1.27 (0.84–1.93)	1.32 (0.92–1.90)	2.66 (2.08–3.39)	<0.001
Skin and soft tissue infection	1.73 (1.45–2.07)	5.86 (4.82–7.13)	0.65 (0.39–1.10)	0.14 (0.05–0.36)	<0.01
Ventilator-associated pneumonia	1.20 (0.96–1.50)	0.63 (0.35–1.14)	1.17 (0.80–1.72)	1.59 (1.18–2.14)	0.01
Catheter-associated UTI	1.06 (0.84–1.34)	0.63 (0.35–1.14)	0.72 (0.44–1.17)	1.62 (1.21–2.18)	0.001
Tracheobronchitis	0.90 (0.70–1.15)	0.40 (0.19–0.85)	0.90 (0.58–1.39)	1.20 (0.86–1.68)	0.01
Non-device UTI	0.43 (0.30–0.61)	0.46 (0.23–0.92)	0.36 (0.18–0.72)	0.46 (0.27–0.78)	0.83
Surgical site infection	0.41 (0.29–0.59)	0.06 (0.00–0.41)	0.40 (0.21–0.77)	0.62 (0.40–0.98)	<0.0001
C. difficile	0.14 (0.08–0.26)	NA*	0.18 (0.07–0.47)	0.19 (0.09–0.43)	0.06
Non-ventilator associated pneumonia	0.13 (0.07–0.24)	0.06 (0.00–0.41)	0.09 (0.02–0.36)	0.19 (0.09–0.43)	0.37
Other infections†	0.45 (0.32–0.64)	0.17 (0.06–0.54)	0.36 (0.18–0.72)	0.69 (0.45–1.07)	0.02

First infection per patient was included. Rates were calculated using Poisson regression and are expressed in incident cases per 1,000 patient/days. P-values were calculated using likelihood ratio tests comparing rates during various periods.

^*No C. difficile infections occurred during the first week after admission.

^†Other infections include cardiovascular infections, other respiratory infections, ear/eyes/nose/throat infections, and non-C. difficile gastrointestinal infections. UTI: urinary tract infection.