Table 3. Comparison of planning target volume (PTV) parameters between carbon-ion radiotherapy and photon therapies, including three-dimensional radiotherapy (3DCRT) or intensisty-modulated radiotherapy (IMRT).
| Carbon-Ion Radiotherapy | 3DCRT | IMRT | |||
|---|---|---|---|---|---|
| (Mean ± SD) | (Mean ± SD) | P-value | (Mean ± SD) | P-value | |
| D2 | 62.2 ± 2.0 Gy (RBE) | 65.0 ± 3.8 Gy | 0.007 | 64.6 ± 1.6 Gy | <0.001 |
| D50 | 61.4 ± 1.8 Gy (RBE) | 60.0 ± 3.1 Gy | 0.154 | 61.3 ± 1.8 Gy | 0.706 |
| D80 | 60.7 ± 1.9 Gy (RBE) | 57.3 ± 3.1 Gy | <0.001 | 58.9 ± 2.3 Gy | 0.009 |
| D95 | 58.8 ± 3.3 Gy (RBE) | 55.0 ± 3.2 Gy | 0.001 | 56.4 ± 2.5 Gy | 0.012 |
| D98 | 57.4 ± 3.9 Gy (RBE) | 54.0 ± 3.3 Gy | 0.005 | 55.0 ± 2.7 Gy | 0.030 |
| HI | 0.08 ± 0.07 | 0.18 ± 0.04 | <0.001 | 0.16 ± 0.05 | <0.001 |
DX, dose covering X% of the planning target volume; RBE, relative biological effectiveness; SD, standard deviation; HI, homogeneity index; 3DCRT, three-dimensional radiotherapy; IMRT, intensity-modulated radiotherapy.