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. 2017 Feb 1;31(5):2065–2075. doi: 10.1096/fj.201601116R

TABLE 2.

Top enriched nephrotoxicity pathways

Toxicity function P Molecules (n)
Renal necrosis/cell death 5.74E-01 to 1.35E-07 152
Renal proliferation 5.22E-01 to 4.29E-05 63
Renal hypertrophy 3.89E-01 to 7.48E-04 14
Glomerular injury (hypertrophy of MCs) 1.00E00 to 1.07E-03 39
Nephrosis 5.22E-01 to 7.73E-03 24