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. Author manuscript; available in PMC: 2018 Jan 20.
Published in final edited form as: Birth Defects Res. 2017 Jan 20;109(1):16–26. doi: 10.1002/bdra.23589

FiGURE 4.

FiGURE 4

Supplementation with a high iron diet does not prevent NTDs in Lrp2null/null mutant embryos. Frequency of NTDs in Lrp2null/null mutant embryos from dams fed control (yellow), high iron (blue) or high folic acid and iron (high FA and Iron; purple) diets for 4 weeks before mating or high iron diet with daily injections of folic acid (high iron + IP FA; blue/orange stripes). Statistical significance was determined by the Fisher’s Exact test and p-values were non significant (ns) for all treatments. The number of samples represented in each group is indicated.