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. Author manuscript; available in PMC: 2018 Jan 30.
Published in final edited form as: Birth Defects Res. 2017 Jan 30;109(2):106–119. doi: 10.1002/bdra.23583

Table 1. Statistically significant metabolites from the comparison of 2ppm FA control vs 2ppm FA VPA-exposed embryo extracts.

Compound Control Mean
(scaled units)* 		VPA Mean
(scaled units)* 		Change from
Control to VPA		 Difference**
(scaled units)* 		P-value
(Corrected)
Adenine 0.86 −0.67 Down 1.52
(95% CI = 1.00 to 2.10)		 7.91 ×10−5
(t-test)
Thymine 0.67 −0.33 Down 1.01
(95% CI = 0.55 to 1.56)		 0.012
(t-test)
*

Metabolite measurements are in z-scaled units.

**

Arithmetic difference between the control mean and the VPA mean for each compound with the 95% CI for the difference included.

n = 18 for each group.