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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2017 May 1;75(1):108–117. doi: 10.1097/QAI.0000000000001301

Fig 2. Activated CD8+ T cells in CSF from acute subjects positively correlates with CSF viral load and CSF markers of neuroinflammation.

Fig 2

A. Correlation of activated CD8+ T cells with viral load in the CSF in AHI Stage 3 participants (n=17). Frequency of activated CD8+ T cells in the CSF does not correlate with plasma viral load (VL) in AHI. B. Frequency of CSF activated CD8+ T cells in AHI Stage 1/2 (dark blue) (n=9) and 3 (green) (n=17) correlates with CSF neuroinflammatory markers neopterin (p=0.005), IP-10 (p=0.016), and CD163 (p<0.0001). C. Frequency of activated CD8+ T cells in the CSF does not correlate with late neuroinflammatory markers (NFL and YKL-40) in acute HIV infection (AHI Stage 1/2 (dark blue) (n=7) and 3 (green) (n=17)).