Table 1.
S. no. | Antibiotic | Concentration (µg) | Class/type of antibiotic | Interpretive criteria for zone diametera (mm) | Antibiotic resistance profile of Haloarcula argentinensis RR10 | |||
---|---|---|---|---|---|---|---|---|
S | I | R | Normal gravity | Simulated microgravity | ||||
1 | Augmentin | 30 | Penicillin + clavulanic acid | – | – | – | S | R |
2 | Norfloxacin | 10 | Fluoroquinolone | ≥17 | 13–16 | 12≤ | S | R |
3 | Nalidixic acid | 30 | Quinolone | ≥19 | 14–18 | 13≤ | R | R |
4 | Imipenem | 10 | Carbapenem | ≥23 | 20–22 | 19≤ | S | S |
5 | Tobramycin | 10 | Aminoglycoside | ≥15 | 13–14 | 12≤ | S | R |
6 | Cefoperazone | 75 | Cephalosporin | ≥21 | 16–20 | 15≤ | S | R |
7 | Cefoxitin | 30 | Cephamycin | ≥18 | 15–17 | 14≤ | S | S |
8 | Piperacillin/tazobactam | 100/10 | β-lactam + β-lactamase inhibitor | ≥21 | 18–20 | 17≤ | S | S |
R resistant, I intermediate, S sensitive, nd not determined
aInterpretive criteria of Gram-negative bacteria as per guidelines of CLSI M100-S24 for disk diffusion