Table 3.
Interventions, blood pressure and laboratory data in cross-over treatment completed cases
| Parameter | HD (n = 68) | I-HDF (n = 68) | P value | Statistics |
|---|---|---|---|---|
| No. of sessions | 816 | 816 | ||
| No. of interventions | 819 | 668 | 0.003 | *, ### |
| Interventions per person (median [IQR]) | 4.5 [0.8–20.3] | 3.0 [0–13.3] | 0.003 | *, ### |
| No. of sessions with hypotension | 337 | 298 | 0.021 | *, ### |
| Predialysis SBP (mmHg) | 134.6 ± 20.8 | 135.3 ± 23.0 | 0.774 | # |
| Intradialytic SBP (mmHg) | 125.7 ± 18.6 | 129.7 ± 19.8 | 0.006 | *, # |
| Postdialysis SBP (mmHg) | 130.0 ± 25.2 | 131.2 ± 26.3 | 0.592 | # |
| DW (kg) | 54.9 ± 10.8 | 54.9 ± 10.8 | 0.852 | # |
| Predialysis weight (kg) | 57.0 ± 11.1 | 57.1 ± 11.2 | 0.534 | # |
| Postdialysis weight (kg) | 55.0 ± 10.7 | 54.9 ± 10.7 | 0.369 | # |
| Predialysis PR (beats/min) | 75.1 ± 12.5 | 76.1 ± 12.3 | 0.628 | # |
| Intradialytic PR (beats/min, at 185 min) | 73.1 ± 12.8 | 70.6 ± 13.9 | 0.007 | *, # |
| Postdialysis PR (beats/min) | 72.4 ± 13.2 | 71.8 ± 14.5 | 0.39 | # |
| Net UF (L/session) | 2.3 ± 0.7 | 2.4 ± 0.7 | 0.588 | # |
| Interdialytic weight gain (% of DW) | 4.3 ± 1.3 | 4.4 ± 1.3 | 0.597 | # |
| Total back-filtrate infusion (mL/session) | 0 | 1362 ± 121 | p < 0.001 | *, # |
| UFR in HD, cUFR in I-HDF (mL/h/kg) | 10.3 ± 3.1 | 19.5 ± 4.2 | p < 0.001 | *, # |
| Membrane area (m2) | 1.68 ± 0.28 | 1.62 ± 0.27 | 0.001 | *, # |
| Membrane material (PS, %) | 82.4 | 100 | p < 0.001 | *, # |
| Hematocrit (%) | 32.9 ± 3.2 | 32.4 ± 3.6 | 0.088 | |
| BUN (mg/dL) | 60.6 ± 13.2 | 61.0 ± 12.5 | 0.845 | |
| Urea reduction ratio (%) | 70.7 ± 7.9 | 68.3 ± 6.2 | p < 0.001 | *, # |
Values are given in mean ± SD in normally distributed, median [IQR interquartile range] in non-normally distributed and % in categorical variables
DW dry weight, PS polysulfone, SBP systolic blood pressure, PR pulse rate, UFR ultrafiltration rate, BUN blood urea nitrogen, cUFR corrected UFR in I-HDF (see text)
### Wilcoxon signed-rank test, ## Chi-square test, # paired t-test, * statistically significant