Table 4.
Characteristics of responders and non-responders to I-HDF
| Responders (n = 34) | Non-responders (n = 34) | P value | Statistics | |
|---|---|---|---|---|
| Delta frequency of intervention [IQR]a | −4 [−8, −2] | 1 [0, 1] | ||
| Age (years) | 68.6 ± 10.7 | 63.6 ± 11.3 | 0.066 | # |
| Male (%) | 50.0 | 52.9 | 0.808 | # |
| Diabetics (%) | 38.2 | 26.4 | 0.299 | ## |
| Vintage (years; median [IQR]) | 4.0[2.0–8.8] | 4.7[1.9–12.8] | 0.605 | ### |
| Dry weight (kg) | 53.8 ± 9.3 | 55.6 ± 12.3 | 0.479 | # |
| Serum albumin (g/dL) | 3.55 ± 0.41 | 3.62 ± 0.36 | 0.453 | # |
| Cardiovascular disease (%) | 47.1 | 35.3 | 0.324 | ## |
| Antihypertensive agent (%) | 47.1 | 52.9 | 0.628 | ## |
| Pressor agent (%) | 38.2 | 14.7 | 0.028 | *, ## |
| Predialysis SBP (mmHg) | 136.2 ± 22.8 | 134.4 ± 23.7 | 0.751 | # |
| Intradialytic SBP increment (mmHg) | 6.9 ± 12.4 | 0.9 ± 9.8 | 0.029 | *, # |
| Pulse rate at 35 min (beats/min) | 70.3 ± 14.4 | 71.0 ± 11.0 | 0.821 | # |
| Net UF (L/session) | 2.46 ± 0.78 | 2.17 ± 0.68 | 0.106 | # |
| cUFR (mL/h/kg) | 20.6 ± 3.4 | 18.3 ± 4.6 | 0.032 | *, # |
| Interdialytic weight gain (% of DW) | 4.8 ± 1.1 | 4.0 ± 1.5 | 0.017 | *, # |
| Membrane area (m2) | 1.69 ± 0.28 | 1.67 ± 0.29 | 0.730 | # |
| Hematocrit (%) | 32.6 ± 4.1 | 32.2 ± 3.0 | 0.599 | # |
| BUN (mg/dL) | 59.6 ± 12.2 | 62.3 ± ±12.8 | 0.382 | # |
| Urea reduction ratio (%) | 71.9 ± 5.0 | 69.5 ± 7.1 | 0.123 | # |
| Blood flow (mL/min) | 200 [200–200] | 200 [200–200] | 0.987 | ### |
| Session time (min) | 239.1 ± 11.6 | 229.4 ± 22.0 | 0.017 | *, # |
| Dialysate buffer (citrate/acetate) | 17/17 | 15/19 | 0.808 | ## |
Values are given in mean ± SD in normally distributed, median [IQR interquartile range] in non-normally distributed and % for categorical variables
BV blood volume, cUFR corrected UFR in I-HDF (see text)
### Wilcoxon signed-test, ## Chi-square test, # t-test, * statistically significant
a(Interventions during I-HDF) − (interventions during HD)