Table 3.
Results of all analyzed 6MWT (data presented as mean ± SD and median)
| Parameters | Units | All 6MWT | Shunt | No shunt | p | WHO-FC I/II | WHO-FC III/IV | p |
|---|---|---|---|---|---|---|---|---|
| N | 164 | 102 | 62 | 124 | 40 | |||
| 6MWD | % of predicted | 74.3 ± 12.6 76.5 |
72.8 ± 12.4
75.2 |
76.9 ± 12.5
79.3 |
0.02 |
77.5 ± 8.9
78.0 |
64.3 ± 16.4
70.6 |
<0.01 |
| Rest SAT | %HbO2 | 92.6 ± 6.3 96 |
89.6 ± 6.4
91 |
97.5 ± 1.1
98 |
<0.01 | 93.1 ± 5.7 6.0 |
90.9 ± 7.8 95.0 |
NS |
| Desaturation | %HbO2 | 11.8 ± 11.2 10.0 |
17.5 ± 10.4
17.5 |
2.6 ± 4.3
1 |
<0.01 | 11.8 ± 11.4 10.0 |
11.7 ± 10.6 9.0 |
NS |
| Rest HR | % of median for age | 101 ± 21 101 |
99.3 ± 2.119 9.3 |
102.9 ± 18.6 103.3 |
NS |
96.6 ± 20.9
96.5 |
113.1 ± 18.5
110.3 |
<0.01 |
| Peak HR | % of max HR for age | 57.1 ± 11.9 56.9 |
57.3 ± 11.1 58.2 |
56.9 ± 13.3 54.9 |
NS |
55.1 ± 11.2
54.3 |
63.1 ± 12.35
9.4 |
<0.01 |
| Peak HR/6MWD | 0.79 ± 0.33 0.75 |
0.81 ± 0.35 0.77 |
0.77 ± 0.29 0.7 |
NS |
0.71 ± 0.2
0.7 |
1.12 ± 0.56
1.05 |
<0.01 | |
| NTproBNP | pg/ml | 875 ± 1904 255 |
804 ± 1612 271 |
995 ± 2336 176 |
NS |
244 ± 244
165 |
2766 ± 3120
1832 |
<0.01 |
| ΔRV-RA | mmHg | 95 ± 25 100 |
101.7 ± 21.8
103 |
83.9 ± 25
82 |
<0.01 | 94.2 ± 27.5 101.0 |
95.8 ± 17 90.5 |
NS |
| LVDd %N | % of mean normal value | 90.8 ± 11.5 92 |
92.8 ± 10.5 94 |
88.7 ± 12.3 91.5 |
NS | 91.1 ± 10.9 93.0 |
90.2 ± 12.1 91.0 |
NS |
| Hb | g/l | 146 ± 18 149 |
152 ± 15
152 |
136 ± 17
132 |
<0.01 | 145 ± 19 149 |
149 ± 14 152 |
NS |
Bold values indicate statistically significant (p < 0.05)