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. 2017 Apr 12;8:220. doi: 10.3389/fphys.2017.00220

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Copyright © 2017 Yang, Ahmari, Schmidt, Redler, Arocha, Pacholec, Magee, Malphurs, Owen, Krane, Li, Wang, Vickroy, Raizada, Martyniuk and Zubcevic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Contraction of Proteobacteria phylum in the b1/2-ARs KO chimera. (A) Taxonomic cladogram was generated by performing linear discriminant analysis (LDA) of effect size (LEfSe) in Galaxy (Segata et al., 2011). Each circle dot represents a bacterial taxon with its diameter proportional to the taxon's relative abundance. Differences are represented in colors where red indicates significant relative abundance in C57 chimera, green indicates significant relative abundance in b1/2-ARs KO chimera, and yellow indicates no significant differences. (B) Unpaired two-tailed t-test analyses of genera with significant differences between b1/2-ARs KO chimera and C57 control chimera. ^* indicates P < 0.05 and ^** indicates P < 0.01.