Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 12;8:217. doi: 10.3389/fphys.2017.00217

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Roy and Finley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Model fit to experimental data. The model predictions for the fold-change in the metabolite concentrations (orange bars) match the experimental measurements from Son et al. (2013) (gray bars). Error bars for the predicted fold-change represent the standard deviation in the model predictions for the best fit from each of the 50 initial conditions. The simulated values of the metabolites derived from the mitochondria and cytoplasm are summed together to determine the total cellular metabolite pool, which was measured in the experiments.