Table 1.

Bounds for initial conditions used in the model simulations.

Metabolite	Lower (mM)	Upper (mM)	Metabolite	Lower (mM)	Upper (mM)
GLC	2.5 × 100	1.4 × 101	GSH	9.9 × 10−2	3.4 × 100
ATP	1.4 × 10−2	1.4 × 101	mPYR	1.2 × 10−2	1.4 × 101
G6P	6.1 × 10−3	2.1 × 100	mAcCoA	1.7 × 10−4	1.7 × 10−1
ADP	2.6 × 10−3	4.8 × 100	mCIT	6.4 × 10−3	1.2 × 100
F6P	3.4 × 10−4	8.4 × 10−1	mICIT	1.0 × 10−2	5.6 × 10−2
FBP	8.5 × 10−3	4.5 × 10−1	mAKG	5.8 × 10−3	2.3 × 10−2
DHAP	2.9 × 10−3	1.2 × 100	mSCoA	1.6 × 10−1	3.0 × 100
G3P	8.0 × 10−4	1.2 × 100	mSUC	1.7 × 10−1	2.8 × 100
NAD	1.8 × 10−2	2.2 × 100	mFUM	1.7 × 10−2	2.2 × 10−1
13BPG	8.0 × 10−4	1.2 × 10−1	mMAL	9.6 × 10−2	2.4 × 100
3PG	8.4 × 10−3	4.9 × 10−1	mOAA	9.6 × 10−2	2.4 × 100
2PG	5.6 × 10−3	6.0 × 10−2	mASP	2.3 × 10−1	7.8 × 100
PEP	1.8 × 10−3	3.8 × 10−1	mGLU	5.6 × 10−3	6.6 × 100
PYR	1.2 × 10−2	1.4 × 101	ASP	2.3 × 10−1	7.8 × 100
LAC	8.0 × 10−2	7.3 × 101	GLU	5.6 × 10−3	6.6 × 100
AMP	3.6 × 10−5	3.4 × 100	OAA	9.6 × 10−2	2.4 × 100
6PG	3.2 × 10−3	1.1 × 10−2	MAL	9.6 × 10−2	2.4 × 100
Ru5P	9.4 × 10−3	7.8 × 10−2	AKG	5.7 × 10−3	2.3 × 10−2
Xyl5P	8.0 × 10−5	1.9 × 10−2	CIT	6.4 × 10−3	1.2 × 100
R5P	3.0 × 10−3	2.2 × 10−2	GLN	1.6 × 10−1	5.6 × 100
E4P	8.0 × 10−5	2.7 × 10−1	NADH	8.0 × 10−4	1.0 × 10−1
S7P	6.5 × 10−3	8.1 × 10−2	NADPH	9.6 × 10−4	6.9 × 10−2
NADP	3.7 × 10−3	4.4 × 10−1	GSSG	1.0 × 10−1	1.1 × 100