Table 2.

Diagnosis of chronic pancreatitis in patients with positive SPFT

	Evidence of chronic pancreatitis in SPFT-positive patients	Time to positive (years)
Patient 1	Changes on MRCP and CT: atrophy of pancreas and mild main pancreatic duct dilatation.	9
Patient 2	Pathology of resected distal pancreas with cystic spaces without epithelial lining surrounded by foamy macrophages, foreign body giant cells, and fibroblasts consistent with pseudocystic change, with surrounding fibrosis consistent with chronic pancreatitis.	1
Patient 3	Changes on MRCP and CT: atrophy of pancreas. Changes on EUS: pancreas parenchyma with contiguous lobularity, hyperechoic foci, hyperechoic strands, dilated main pancreatic duct, main pancreatic duct with hyperechoic walls.	9
Patient 4	Pathology of pancreas from Whipple specimen with dense periductal fibrosis with admixed lymphocytes and eosinophils and complete atrophy of acinar tissue seen adjacent to an intraductal papillary mucinous neoplasm.	1
Patient 5	Changes on EUS: pancreas parenchyma with contiguous lobularity, hyperechoic foci, and hyperechoic strands and cysts. Main pancreatic duct with hyperechoic walls, and irregular margins. Dilated side branches.	5
Patient 6	Changes on MRCP: pancreas divisum and main-duct irregularities. Changes on EUS: pancreas parenchyma with contiguous lobularity, hyperechoic foci, and hyperechoic strands. Main pancreatic duct with hyperechoic walls. Dilated side branches.	11
Patient 7	Pathology of pancreas from Whipple specimen with focal complete atrophy of acinar tissue with isolated, entrapped residual pancreatic ductules embedded within a collagenized, scar-like stroma.	2
Patient 8	Changes on MRCP: atrophy of pancreas, main pancreatic duct irregularity and stricture, pseudocyst.	1
Patient 9	Changes on MRCP: atrophy of pancreas. Changes on EUS: pancreas parenchyma with contiguous lobularity and cysts. Main pancreatic duct with hyperechoic walls and irregular margins. Atrophic pancreas.	4

CT, computed tomography; EUS, endoscopic ultrasound; MRCP, magnetic resonance cholangiopancreatography; SPFT, secretin pancreatic function test.