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. 2017 Mar 30;13:625–638. doi: 10.3762/bjoc.13.61

Scheme 16.

Scheme 16

(a) DABCO-mediated intramolecular cyclization of N-(propargylcarbamothioyl)amides 53 to the corresponding dihydrothiazol-2-ylamides 54. (b) Possible reaction pathway for the generation of product 54.