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. 2017 Mar 21;114(14):E2826–E2835. doi: 10.1073/pnas.1613447114

Table 1.

Activation of IDE by myo-InsPs

Myo-inositol Maximal fold activation, mean ± SD KA, µM, mean ± SD
3-monophosphate 6.2 ± 0.8 94.5 ± 21.5
1,2-bisphosphate 3.1 ± 0.4 56.8 ± 17.4
1,3-bisphosphate 6.1 ± 0.5 27.2 ± 6.0
4,5-bisphosphate 13.8 ± 3.4 83.3 ± 24.2
1,3,5-trisphosphate 12.9 ± 0.7 7.8 ± 0.8
1,4,5-trisphosphate 30.6 ± 1.4 39.9 ± 4.3
1,3,4,5-tetrakisphosphate 58.6 ± 1.5 18.7 ± 1.5
1,3,4,5,6-pentakisphosphate 83.3 ± 4.0 8.2 ± 1.5
1,2,3,4,5,6-hexakisphosphate (phytic acid) 72.0 ± 4.0 0.7 ± 0.1
1-diphosphoinositol pentakisphosphate 79.7 ± 3.1 0.9 ± 0.1
5-diphosphoinositol pentakisphosphate 94.7 ± 4.1 1.7 ± 0.2