Table 3.

Effect of phytic acid on the hydrolysis of physiological peptides by IDE

Substrate	Rate, nmol/min/mg IDE
	No addition	Plus phytic acid (fold increase)
Angiotensin	6.1	38.3 (6.3)
Bradykinin	9.6	254 (26.4)
Dynorphin B9	35	340 (9.7)
Insulin	22.4	22.4 (1.0)
β-endorphin	1,400	1,200 (0.86)
Amyloid β peptide (1–40)	1,500	2,720 (1.8)
Glucagon	3,200	2,672 (0.8)

The concentration of phytic acid, when present, was 5 μM.