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. 2017 Mar 20;114(14):E2920–E2928. doi: 10.1073/pnas.1619529114

Table 1.

Top-40 up-regulated genes in ΔscmR relative to WT determined by RNA-seq analysis

Locus tag Fold change Gene Joint Genome Institute product name
BTH_I2366 135.0 bhcB Polyketide synthase
BTH_I2367 123.7 bhcA Dihydroaeruginoic acid synthetase
BTH_I2365 123.1 bhcC Polyketide synthase
BTH_I2363 113.3 bhcE Polyketide synthase
BTH_I2362 98.6 bhcF Acyl-CoA dehydrogenase domain protein
BTH_I2360 95.7 bhcH Nonribosomal peptide synthetase, putative
BTH_I2361 95.2 bhcG Phosphotransferase enzyme family protein, putative
BTH_I2359 91.2 bhcI Pyridine nucleotide-disulfide oxidoreductase, class II
BTH_I2358 64.3 bhcJ Lipase/esterase
BTH_I2368 52.0 bhcAa Hypothetical protein
BTH_I2357 50.8 bhcK Thioesterase type II
BTH_I2369 18.8 Transcriptional regulator, AraC family domain protein
BTH_II2091 17.8 malD Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, putative
BTH_II2089 16.2 malB Hypothetical protein
BTH_I3247 16.1 Aldehyde dehydrogenase family protein
BTH_I2356 15.5 Serine protease, subtilase family
BTH_II2090 14.9 malC Syringomycin synthesis regulator SyrP, putative
BTH_I2480 14.7 Sulfate ABC transporter, periplasmic sulfate-binding protein
BTH_I2450 13.9 Amino acid ABC transporter substrate-binding protein, PAAT family
BTH_I1849 13.6 Two component transcriptional regulator, LuxR family
BTH_II2093 13.2 malF Polyketide synthase, putative
BTH_II1234 12.6 btaL JamP
BTH_II2096 12.5 malI Long-chain-fatty-acid–CoA ligase, putative
BTH_II1236 12.0 btaN Nonribosomal peptide synthetase, putative
BTH_II2092 11.8 malE Aldehyde dehydrogenase family protein
BTH_II2088 11.0 malA Thiotemplate mechanism natural product synthetase
BTH_II2095 10.8 malH Diaminopimelate decarboxylase, putative
BTH_II2097 10.6 malJ Lipoprotein, putative
BTH_II1237 10.0 btaO Thiotemplate mechanism natural product synthetase
BTH_II2099 9.7 malL AMP-binding domain protein
BTH_I0892 9.7 Hypothetical protein
BTH_I0815 9.5 Bacterial protein of unknown function (DUF934) superfamily
BTH_II2098 9.2 malK Malonyl CoA-acyl carrier protein transacylase
BTH_I1051 9.0 Sulfate transporter, putative
BTH_II1240 8.9 btaS Thioesterase II of alpha/beta hydrolase superfamily
BTH_II1238 8.5 btaP Polyketide synthase
BTH_II2094 8.5 malG Ketol-acid reductoisomerase (EC 1.1.1.86)
BTH_II1241 7.8 btaT Drug resistance transporter, Bcr/CflA family protein, putative
BTH_II1239 7.8 btaQ Acetyltransferase, GNAT family
BTH_I0814 7.7 Sulfite reductase (NADPH) beta subunit (EC 1.8.1.2)