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| PDE | GEBR-32a IC50 (μM) |
|---|---|
| PDE4D1 | 4.97 |
| PDE4D2 | 2.89 |
| PDE4D3 | 2.43 |
| PDE4D5 | 3.18 |
| PDE4D7 | 1.14 |
GEBR-32a has been tested at five different concentrations (1nM-100 μM) on human recombinant PDE4D isoforms expressed in baculovirus. IC50s have been obtained by non-linear regression analysis of the concentration-inhibition curves.
