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Immunohistochemical staining of Cd3-positive T cells associated with necrotic foci in representative hematoxylin and eosin liver sections from Wt, Gsta4−/−, Ppara−/−, and Gsta4−/−/Ppara−/− double-knockout (dKO) mice receiving either chow or 70% HF diets for 12 weeks. Immunhohistochemistry was performed as described in Materials and Methods. CV, central vein; PT, portal triad.
