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. 2005 Jan;73(1):459–463. doi: 10.1128/IAI.73.1.459-463.2005

FIG. 3.

FIG. 3.

Effect of inactivation of degS on the ability of Salmonella serovar Typhimurium to infect mice. (A) Comparison of the abilities of serovar Typhimurium degS and rpoE mutants to survive in vivo in murine organs following parenteral administration. Groups of five female BALB/c mice were challenged i.p. with 105 CFU of either the rpoE or the degS mutant. After 24 h, bacteria in the spleens and livers were enumerated. Each filled circle represents the count from the organ of an individual mouse. (B) Effect of the degS mutation on the ability of serovar Typhimurium to infect mice via the oral route. Mice were challenged orally with either 5 × 105 CFU of the WT strain or 1.6 ×108 CFU of the degS mutant, and the numbers of bacteria present in different organs were determined 7 days later. Each bar represents the mean for four mice; error bars, standard deviations. The error bars for livers and spleens of the degS group are too small to be visible. PP, Peyer's patches; MLN, mesenteric lymph nodes.