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. 2017 Jan 13;45(6):3568–3579. doi: 10.1093/nar/gkw1351

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Global view of the molecule highlighting the conformation variability. (A) Sequence of HP1 showing the four regions and highlighting the bulged nucleotides (triangles) forming triple interactions in the helical stack (blue triangle turned inwards) or facing the solvent (triangle outwards) with U41 (magenta), U72 (green) and U76 (orange). Green dotted lines connect the bulged residues with their coplanar base-pairs. (B) Molecule B (grey sticks) in the Au-map contoured at 1.0 σ. (C) Superposition of several molecules (molecule A from Au-, Os- and native maps) showing position variation at U72 or U41. (D) Conformation OUT, as observed in molecule A of Au-map. (E) Conformation IN, as observed in molecule A of Au-map.