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. 2017 Jan 13;45(6):3568–3579. doi: 10.1093/nar/gkw1351

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — The uridines at the 7SK motif. The (GAUC) repeat and uridines U40 (cyan), U41 (magenta) and U63 (orange). (A) Axial view of conformation OUT in molecule A (Os-map). The black arrow represents the helical axis and shows the direction of the apical loop. (B) Same view for conformation IN. (C) Perpendicular view for conformation OUT. (D) Perpendicular view for conformation IN. H-bonds of the Hoogsteen base-pair are indicated with dotted lines.