Figure 2.

Mutations in the top strand of the SW_HEL VDJ_H sequence window were averaged per host mouse (dots), with the overall mean of hosts (± 95% confidence interval) indicated by histograms. Significant differences (according to Tukey's ordinary one-way ANOVA) compared to (‘cf.’) the UNG⁺M⁺ or UNG^–M^– datasets are indicated: ****p < 0.0001; ***p < 0.001; **p < 0.01; *p < 0.05; n.s., not significant. Mutations are divided into three classes: (A) transition mutations at C or G; (B) transversion mutations at C or G; (C) any mutation at A or T.