Table 3. Number of correctly identified downregulated transcripts by miRNAs used in the pSILAC experiment carried out in HeLa cells which have overlapping Ago2 CLIPed binding sites in the presented cell lines.
| miR-1 | miR-16 | miR-30a | miR-155 | Let-7b | Total | |
|---|---|---|---|---|---|---|
| 293s | 59 (0.22) | 120 (0.46) | 65 (0.4) | 73 (0.24) | 98 (0.27) | 415 (0.31) |
| BC1 | 155 (0.60) | 113 (0.43) | 62 (0.82) | 131 (0.44) | 193 (0.53) | 654 (0.56) |
| EF3D | 97 (0.37) | 61 (0.23) | 23 (0.14) | 126 (0.42) | 101 (0.27) | 408 (0.28) |
| Lymphoblastic | 29 (0.11) | 46 (0.17) | 19 (0.11) | 43 (0.14) | 32 (0.08) | 169 (0.12) |
| hESC | 28 (0.10) | 20 (0.07) | 13 (0.08) | 6 (0.02) | 47 (0.12) | 114 (0.07) |
The first number in each column represents the frequency of the binding sites which are correctly identified by miRTar2GO in HeLa cell and have an overlapping binding site in the CLIP data of the corresponding cell type. Each number in parenthesis shows the percentage of the correctly identified downregulated target by miRTar2GO in HeLa cell which has an overlapping binding site in the associated cell line. The first number of the last column represents the total number of downregulated transcripts in HeLa cells which are identified by miRTar2GO and have an overlapping Ago2–mRNA footprint in the associated cell line. The second number in the last column represents the percentage of correctly identified downregulated target by miRTar2GO in HeLa cells.