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(A and B) UV-melting profiles of quadruplexes 5–14 as well as the unmodified control measured at 295 nm in 10 mM Tris, pH 6.8 (A) with and (B) without 25 mM KCl at a final concentration of 8 μM. (C and D) CD spectra of quadruplexes 5–14 recorded at 15°C in 10 mM Tris, pH 6.8 (C) with and (D) without 25 mM KCl at a final concentration of 8 μM.
